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Newrotex develops innovative silk-based medical
solutions for the nervous system.
Newrotex develops innovative silk-based medical
solutions for the nervous system.
The answer to “Can you repair nerves?” shouldn’t come with caveats. This is why Newrotex is set to disrupt existing approaches to surgical nerve repair. We’re on track to provide an alternative to autografts, the current gold standard in treatment for nerve injuries. A gold standard that requires sacrificing a healthy nerve from another part of the body. With our patented silk-based technology, we’ll deliver an off-the-shelf solution for surgical repair of the nerve. Without the need for long, complicated operations or using expensive donor tissues, Newrotex makes immediate treatment possible for patients who have suffered nerve injuries due to trauma, medical conditions, or surgical treatments.
Annual operations for nerve injuries
Newrotex silk-based nerve products address the shortcomings of the solutions currently available.
Most of the world’s 1.5 million annual operations for nerve injuries are treated with autografts requiring a second injury and long surgery times, along with risking donor site morbidity and infection.
All of the major current solutions – autografts, allografts, and hollow tube conduits – are limited when repairing large gaps in nerves. Read Current Approaches for more about these and other shortcomings with current solutions for peripheral nerve repair.
Over the past few decades, the potential biomedical applications of silk have been gaining interest at an exponential rate.
The versatility created by silk’s chemical structure allows for the production of fibres, gels, scaffolds, films, membranes, and powders. Silk has shown to have excellent cell affinity, and being biocompatible, with the ability to tailor biodegradation, silk is an ideal candidate for biomedical applications.
In terms of nerve repair, luminal silk fibres inside a vein or conduit guide regenerating axons, while the bioabsorbable, permeable tube allows nutrients to support nerve regeneration. Furthermore, silk products can be stored at room temperature, thereby removing the need for expensive cold storage and transportation.
Our first product is a 10cm implant made from bundles of luminal spider silk fibres that can be implanted into a vein or inserted into hollow conduits to support nerve re-growth. Pre-clinical studies have show that SilkAxons® support superior axonal regeneration.
Our second product is an off-the-shelf silk-based peripheral nerve conduit pre-filled with enhancing luminal silk fibres, negating the need to use a vein.
The fibres have proven nerve-regenerating properties and clinical trials show them to be comparable or superior to autografts. And with a porous tubular biocompatible sheath designed to encourage vascularisation, we provide a new and better approach to treating patients with peripheral nerve injuries.
Newrotex launched a first-in-human clinical trial in Q3 2025 using SilkAxons® to bridge large nerve gaps of up to 10cm (significantly more than current FDA approved devices). This study will generate foundational data for Newrotex’s global clinical strategy. Our goal is to commence a large study this year culminating in an application for market approval in the USA and UK. We are also developing collaborations in which our silk platform technology may lead to further improvements in patient care, such as Schwann cell delivery and spinal cord injury repair.
The search for an "index" of the movie (1993) typically refers to a comprehensive overview of its production details, cast, and impact. This legal drama, directed by Rajkumar Santoshi , is a landmark in Indian cinema known for its social commentary and iconic performances. Damini (1993) - Movie Index Title: Damini (Translates to Lightning ) Release Year: 1993 Genre: Legal Drama / Social Thriller Director & Co-Writer: Rajkumar Santoshi Lead Cast:
as Tolu: The antagonist, brother-in-law of Damini who commits the crime. Kulbhushan Kharbanda as Mr. Gupta: Shekhar’s father. Aamir Khan in a Special Appearance. 3. Plot Summary
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Damini had a significant impact on Indian cinema, as it addressed several social issues, including corruption, patriarchy, and social injustice. The movie inspired a new wave of films that tackled bold and socially relevant themes. The search for an "index" of the movie
as Damini Gupta: The titular character, a determined woman fighting for the dignity of her housemaid.
Amazon Prime Video also offers Damini for streaming in various regions. The platform's listing includes the full runtime of 2 hours and 55 minutes and provides both rental and purchase options depending on your location. Kulbhushan Kharbanda as Mr
In conclusion, the "index of Damini movie" provides a comprehensive guide to this landmark Bollywood film. From its plot and cast to its production and reception, "Damini" is a movie that has left an indelible mark on Indian cinema. Its cultural significance and legacy continue to be felt today, and it remains one of the most iconic and influential films of Bollywood.
The film was both a commercial blockbuster and a critical darling, sweeping major awards in 1993–1994:
The film brought crucial conversations about women's safety, societal hypocrisy, and legal corruption into mainstream Indian households. Where to Watch Legally
The story revolves around (played by Meenakshi Seshadri), a righteous woman who marries into a wealthy family. Her life takes a dark turn when she witnesses her brother-in-law and his friends sexually assaulting the family's maid on the night of Holi.